Wyoming is often known for Yellowstone and Grand Teton, but southern Wyoming is packed with hidden gems that are closer and quieter — perfect for a Denver to Wyoming road trip. You’ll explore Cheyenne, Laramie and Saratoga, three towns rich in Western heritage, expansive landscapes and vibrant restaurants.

Day 1: Cheyenne – Wyoming’s Capital 

Drive Time: 90 minutes (via I-25 from Denver)

Start your weekend trip off right by hitting the road early to avoid any traffic on I-25. As you pass onto the Wyoming border, be sure to stop at Terry Bison Ranch and take a narrated bison train tour to see Wyoming’s state mammal up close. The hand-built trains take visitors (safely) on an hour-long ride to see its bison herd.

Morning: Explore Downtown Cheyenne

Stroll through the heart of Cheyenne and take in its rich history by starting at the Wyoming State Capitol, one of 20 capitols designated as a National Historic Landmark. A striking example of classical architecture, the Wyoming Capitol is open Monday through Friday for self-guided tours.

Continue into Cheyenne’s historic downtown, where you’ll find The Wrangler, an Instagram-worthy stop. A beloved Western outfitter, it’s your one-stop shop for cowboy boots, hats and everything in between to really embrace the Western lifestyle. Just a short walk away, you’ll find Paramount Café, a cozy spot for a coffee break that was once a theater that entertained Cheyenne’s early residents.

Cheyenne is home to incredible Western artists and makers. Here are a few other downtown shops to not miss:

• Alexis Drake – Luxury leather handbags and accessories
• Westward – Western-inspired art and goodies
• 307 Made – Wyoming locally made products and gifts

Lunch Stop

Nestled right in front of Cheyenne’s Depot, The Albany – a local institution, has been serving locals and visitors alike for nearly 80 years. With options like a hot beef or BBQ tofu sandwich, The Albany offers a wide array of comfort food and western vibes.

Afternoon: Cheyenne’s Unexpected Side

​Have you ever imagined exploring a site that once controlled nuclear missiles? Just north of Cheyenne lies the Quebec 01 Missile Alert Facility, a Cold War relic that offers a unique glimpse into military history. Constructed in 1962 as a Minuteman I Launch Control site, it was later upgraded to house the Peacekeeper missile system in 1986. The facility remained operational until 2005 and was opened to the public as a state historic site. Visitors can embark on self-guided tours to explore the control rooms, complete with original equipment, and view various artifacts that highlight the site's pivotal role during the Cold War.

In contrast to military history, make your way back to Cheyenne to take a relaxing stroll through Cheyenne Botanic Gardens. Serving as a community cornerstone, the botanic gardens sites on nine acres and include the Shane Smith Grand Conservatory - a tropical paradise with a 34-foot-tall palm tree and the Paul Smith Children's Village where littles can interact and learn from sustainable landscapes.

Dinner & Stay

After a day of exploration, finish the day with either Wyoming’s Rib & Chop House or The Metropolitan Downtown, both offering modern, western cuisine. To cap off the night, unwind with a craft cocktail at Chronicles Distilling, a veteran-owned distillery specializing in small-batch spirits, or sip on a locally brewed beer at Blacktooth Brewery, known for its award-winning craft beers and laid-back vibe. Finally, settle in at Little America Hotel and Resort for a restful night before another day of adventure.

Day 2: Laramie & Saratoga: Wyoming’s Mountain Getaway

Drive Time: 3 Hours

Morning

Fuel up at the Luxury Diner in Cheyenne, a railcar diner known for its hearty breakfasts and giant cinnamon rolls. Once you’re ready to hit the road, head west toward Laramie via Happy Jack Road. Start the day with a tour of the Wyoming Territorial Prison State Historic Site, a fascinating landmark that once held the infamous Butch Cassidy. Make your way to Laramie’s historic downtown, known for its locally owned shops and colorful murals, including:

• The Bent and Rusty – Antiques and handcrafted gifts
• Range Leather Co.  – Handcrafted leather goods
• Poppy’s – Flower shop & women’s boutique
• Sugar Mouse Cupcake House – Cupcakes and tea shop

Lunch Stop

Head to Sweet Melissa, a beloved vegetarian restaurant offering creative dishes, including locals’ favorites like the black bean burger or the butternut squash enchiladas. Or try the Crowbar and Grill, another local spot with hand-tossed pizzas and hand-cut fries daily.

Scenic Drive to Saratoga

After lunch, embark on one of Wyoming’s most breathtaking drives—the Snowy Range Scenic Byway (WY-130). This stunning mountain pass winds through the Medicine Bow National Forest, offering panoramic views of rugged peaks, alpine lakes and wildflower-covered meadows. Stop along the way at Lake Marie or Mirror Lake to stretch your legs and take in the beauty.

Dinner & Stay

Once you arrive in Saratoga, check into Saratoga Hot Springs Resorts and find your way to the teepee-covered mineral hot springs. A soak in these therapeutic waters is the perfect way to ease any road trip fatigue. Finish the day by enjoying Bella’s Bistro, an intimate eatery of traditional Italian dishes. This in-demand restaurant encourages reservations a week or two in advance.

Day 3:

Morning

Grab a quick breakfast sandwich and Cowbell coffee at Saratoga Sandwich Company before a morning on the trails. Mountain bike and UTV rentals are available at Saratoga Hot Springs Resort to explore even further into the Snowy Range. Or chat with a guide from Wyoming Adventure Guides to give you the best advice on trail conditions for hiking as well.

If you’d prefer to stay closer to town, take a scenic float trip on a kayak down the Upper North Platte River.

Plan Your Wyoming Getaway Today

Looking for more travel inspiration? Find the top places to visit in Cheyenne, Laramie and Saratoga, and order Wyoming’s Official Travel Guide to start planning today.